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1

Relative Incidence of ESRD Versus Cardiovascular Mortality in Proteinuric Type 2 Diabetes and Nephropathy: Results From the DIAMETRIC (Diabetes Mellitus Treatment for Renal Insufficiency Consortium) Database

David K. Packham, Tahira P. Alves, Jamie P. Dwyer, Robert Atkins, Dick de Zeeuw, Mark Cooper, Shahnaz Shahinfar, Julia B. Lewis, Hiddo J. Lambers Heerspink

Journal:

American Journal of Kidney Diseases

Year:

2012

Language:

english

File:

PDF, 622 KB

english, 2012

2

Sulodexide for Kidney Protection in Type 2 Diabetes Patients With Microalbuminuria: A Randomized Controlled Trial

Edmund J. Lewis, Julia B. Lewis, Tom Greene, Lawrence G. Hunsicker, Tomas Berl, Marc A. Pohl, Dick de Zeeuw, Hiddo Lambers Heerspink, Richard D. Rohde, Robert C. Atkins, Anne T. Reutens, David K. Pack

Journal:

American Journal of Kidney Diseases

Year:

2011

Language:

english

File:

PDF, 825 KB

english, 2011

3

Aspirin Is Beneficial in Hypertensive Patients With Chronic Kidney Disease: A Post-Hoc Subgroup Analysis of a Randomized Controlled Trial

Meg J. Jardine, Toshiharu Ninomiya, Vlado Perkovic, Alan Cass, Fiona Turnbull, Martin P. Gallagher, Sophia Zoungas, Hiddo J. Lambers Heerspink, John Chalmers, Alberto Zanchetti

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

4

Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention

Gansevoort, Ron T, Correa-Rotter, Ricardo, Hemmelgarn, Brenda R, Jafar, Tazeen H, Heerspink, Hiddo J Lambers, Mann, Johannes F, Matsushita, Kunihiro, Wen, Chi Pang

Journal:

Year:

2013

Language:

english

File:

PDF, 1.10 MB

english, 2013

5

Management of hyperkalaemia consequent to mineralocorticoid-receptor antagonist therapy

Roscioni, Sara S., de Zeeuw, Dick, Bakker, Stephan J. L., Lambers Heerspink, Hiddo J.

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2012

Language:

english

File:

PDF, 208 KB

english, 2012

6

Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): a randomised clinical trial

de Zeeuw, Dick, Anzalone, Deborah A, Cain, Valerie A, Cressman, Michael D, Heerspink, Hiddo J Lambers, Molitoris, Bruce A, Monyak, John T, Parving, Hans-Henrik, Remuzzi, Giuseppe, Sowers, James R, Vid

Journal:

The Lancet Diabetes & Endocrinology

Year:

2015

Language:

english

File:

PDF, 311 KB

english, 2015

7

Intensive glucose control improves kidney outcomes in patients with type 2 diabetes

Perkovic, Vlado, Heerspink, Hiddo Lambers, Chalmers, John, Woodward, Mark, Jun, Min, Li, Qiang, MacMahon, Stephen, Cooper, Mark E, Hamet, Pavel, Marre, Michel, Mogensen, Carl Erik, Poulter, Neil, Manc

Journal:

Kidney International

Year:

2013

Language:

english

File:

PDF, 411 KB

english, 2013

8

The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials

Czernichow, Sébastien, Zanchetti, Alberto, Turnbull, Fiona, Barzi, Federica, Ninomiya, Toshiaru, Kengne, André-Pascal, Lambers Heerspink, Hiddo J, Perkovic, Vlado, Huxley, Rachel, Arima, Hisatomi, Pat

Journal:

Journal of Hypertension

Year:

2011

Language:

english

File:

PDF, 761 KB

english, 2011

9

Is the randomized controlled drug trial in Europe lagging behind the USA?

Hiddo J. Lambers Heerspink, Mirjam J. Knol, Robert J. W. Tijssen, Thed N. Van Leeuwen, Diederick E. Grobbee, Dick De Zeeuw

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 627 KB

english, 2008

10

Does the European Clinical Trials Directive really improve clinical trial approval time?

Hiddo J. Lambers Heerspink, Daniela Dobre, Hans L. Hillege, Diederick E. Grobbee, Dick De Zeeuw

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 445 KB

english, 2008

11

Effect of Frozen Storage on Urinary Concentration of Kidney Damage Markers

Ferdau L. Nauta, Stephan J.L. Bakker, Hiddo Lambers Heerspink, Dick de Zeeuw, Wim van Oeveren, Henk Bilo, Paul E. de Jong, Ron T. Gansevoort

Journal:

American Journal of Kidney Diseases

Year:

2012

Language:

english

File:

PDF, 286 KB

english, 2012

12

Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials

Hiddo J Lambers Heerspink, Toshiharu Ninomiya, Sophia Zoungas, Dick de Zeeuw, Diederick E Grobbee, Meg J Jardine, Martin Gallagher, Matthew A Roberts, Alan Cass, Bruce Neal, Vlado Perkovic

Journal:

Year:

2009

Language:

english

File:

PDF, 204 KB

english, 2009

13

Blood pressure in dialysis patients—look before we leap – Authors' reply

Vlado Perkovic, Hiddo Lambers Heerspink, Toshiharu Ninomiya, Alan Cass, Bruce Neal

Journal:

Year:

2009

Language:

english

File:

PDF, 89 KB

english, 2009

14

Composite renal endpoints: was ACCOMPLISH accomplished?

Hiddo Lambers Heerspink, Dick de Zeeuw

Journal:

Year:

2010

Language:

english

File:

PDF, 111 KB

english, 2010

15

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis

Caroline S Fox, Kunihiro Matsushita, Mark Woodward, Henk JG Bilo, John Chalmers, Hiddo J Lambers Heerspink, Brian J Lee, Robert M Perkins, Peter Rossing, Toshimi Sairenchi, Marcello Tonelli, Joseph A

Journal:

Year:

2012

Language:

english

File:

PDF, 553 KB

english, 2012

16

SODIUM INTAKE AND RISK OF CORONARY HEART DISEASE IN THE OVERALL POPULATION AND SPECIFIC SUBPOPULATIONS

Michel Joosten, Ron Gansevoort, Hiddo Lambers Heerspink, Johanna Geleijnse, Edith Feskens, Gerjan Navis

Journal:

Kidney Research and Clinical Practice

Year:

2012

Language:

english

File:

PDF, 142 KB

english, 2012

17

Debate: PRO Position. Should Microalbuminuria Ever Be Considered as a Renal Endpoint in Any Clinical Trial

Lambers Heerspink, Hiddo J., de Zeeuw, Dick

Journal:

American Journal of Nephrology

Year:

2010

Language:

english

File:

PDF, 258 KB

english, 2010

18

Rationale and Trial Design of Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes: The Occurrence of Renal Events (BEACON)

de Zeeuw, Dick, Akizawa, Tadao, Agarwal, Rajiv, Audhya, Paul, Bakris, George L., Chin, Melanie, Krauth, Melissa, Lambers Heerspink, Hiddo J., Meyer, Colin J., McMurray, John J., Parving, Hans-Henrik,

Journal:

American Journal of Nephrology

Year:

2013

Language:

english

File:

PDF, 268 KB

english, 2013

19

Improving the efficacy of RAAS blockade in patients with chronic kidney disease

Lambers Heerspink, Hiddo J., de Borst, Martin H., Bakker, Stephan J. L., Navis, Gerjan J.

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2012

Language:

english

File:

PDF, 281 KB

english, 2012

20

An acute fall in estimated glomerular filtration rate during treatment with losartan predicts a slower decrease in long-term renal function

Holtkamp, Frank A, de Zeeuw, Dick, Thomas, Merlin C, Cooper, Mark E, de Graeff, Pieter A, Hillege, Hans J L, Parving, Hans-Henrik, Brenner, Barry M, Shahinfar, Shahnaz, Lambers Heerspink, Hiddo J

Journal:

Kidney International

Year:

2011

Language:

english

File:

PDF, 197 KB

english, 2011

21

Age and Sex Effects on the Single- and Multiple-dose Safety and Pharmacokinetics of the New Rennin Inhibitor ACT-178882

de Vries, Dick E., Lambers Heerspink, Hiddo J.

Journal:

Cardiovascular Therapeutics

Year:

2013

Language:

english

File:

PDF, 28 KB

english, 2013

22

The effect of RAAS blockade on the progression of diabetic nephropathy

Roscioni, Sara S., Heerspink, Hiddo J. Lambers, de Zeeuw, Dick

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2013

Language:

english

File:

PDF, 914 KB

english, 2013

23

Estimated Albumin Excretion Rate Versus Urine Albumin-Creatinine Ratio for the Assessment of Albuminuria: A Diagnostic Test Study From the Prevention of Renal and Vascular Endstage Disease (PREVEND) Study

Abdelmalek, Joseph A., Gansevoort, Ron T., Lambers Heerspink, Hiddo J., Ix, Joachim H., Rifkin, Dena E.

Journal:

American Journal of Kidney Diseases

Year:

2014

Language:

english

File:

PDF, 296 KB

english, 2014

24

National Kidney Foundation Primer on Kidney Diseases || Pathogenesis, Pathophysiology, and Treatment of Diabetic Nephropathy

Lambers Heerspink, Hiddo J.

Year:

2014

Language:

english

File:

PDF, 2.27 MB

english, 2014

25

Are Renin–Angiotensin–Aldosterone System Inhibitors Lifesaving in Chronic Kidney Disease?∗

Damman, Kevin, Lambers-Heerspink, Hiddo J.

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 78 KB

english, 2014

26

Therapeutic Approaches in Lowering Albuminuria: Travels Along the Renin-Angiotensin-Aldosterone-System Pathway

Lambers Heerspink, Hiddo J.

Journal:

Advances in Chronic Kidney Disease

Year:

2011

Language:

english

File:

PDF, 237 KB

english, 2011

27

Albuminuria, Estimated GFR, Traditional Risk Factors, and Incident Cardiovascular Disease: The PREVEND (Prevention of Renal and Vascular Endstage Disease) Study

Smink, Paul A., Lambers Heerspink, Hiddo J., Gansevoort, Ron T., de Jong, Paul E., Hillege, Hans L., Bakker, Stephan J.L., de Zeeuw, Dick

Journal:

American Journal of Kidney Diseases

Year:

2012

Language:

english

File:

PDF, 491 KB

english, 2012

28

Short-term vitamin D3 supplementation lowers plasma renin activity in patients with stable chronic heart failure: An open-label, blinded end point, randomized prospective trial (VitD-CHF trial)

Schroten, Nicolas F., Ruifrok, Willem P.T., Kleijn, Lennaert, Dokter, Martin M., Silljé, Herman H., Lambers Heerspink, Hiddo J., Bakker, Stephan J.L., Kema, Ido P., van Gilst, Wiek H., van Veldhuisen,

Journal:

American Heart Journal

Year:

2013

Language:

english

File:

PDF, 345 KB

english, 2013

29

Estimated GFR Decline as a Surrogate End Point for Kidney Failure: A Post Hoc Analysis From the Reduction of End Points in Non–Insulin-Dependent Diabetes With the Angiotensin II Antagonist Losartan (RENAAL) Study and Irbesartan Diabetic Nephropathy Trial (IDNT)

Lambers Heerspink, Hiddo J., Weldegiorgis, Misghina, Inker, Lesley A., Gansevoort, Ron, Parving, Hans-Henrik, Dwyer, Jamie P., Mondal, Hasi, Coresh, Josef, Greene, Tom, Levey, Andrew S., de Zeeuw, Dic

Journal:

American Journal of Kidney Diseases

Year:

2014

Language:

english

File:

PDF, 630 KB

english, 2014

30

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

Vimaleswaran, Karani S, Cavadino, Alana, Berry, Diane J, Jorde, Rolf, Dieffenbach, Aida Karina, Lu, Chen, Alves, Alexessander Couto, Heerspink, Hiddo J Lambers, Tikkanen, Emmi, Eriksson, Joel, Wong, A

Journal:

The Lancet Diabetes & Endocrinology

Year:

2014

Language:

english

File:

PDF, 363 KB

english, 2014

31

Do diabetic kidneys deserve a lifestyle change?

de Zeeuw, Dick, Heerspink, Hiddo Lambers

Journal:

The Lancet Diabetes & Endocrinology

Year:

2014

Language:

english

File:

PDF, 99 KB

english, 2014

32

Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease

de Zeeuw, Dick, Akizawa, Tadao, Audhya, Paul, Bakris, George L., Chin, Melanie, Christ-Schmidt, Heidi, Goldsberry, Angie, Houser, Mark, Krauth, Melissa, Lambers Heerspink, Hiddo J., McMurray, John J.,

Journal:

New England Journal of Medicine

Year:

2013

Language:

english

File:

PDF, 651 KB

english, 2013

33

Chronic Renal Disease || Albuminuria

Lambers Heerspink, Hiddo J.

Year:

2015

Language:

english

File:

PDF, 877 KB

english, 2015

34

Visit-to-Visit Variability in Blood Pressure and Kidney and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Nephropathy: A Post Hoc Analysis From the RENAAL Study and the Irbesartan Diabetic Nephropathy Trial

McMullan, Ciaran J., Lambers Heerspink, Hiddo J., Parving, Hans-Henrik, Dwyer, Jamie P., Forman, John P., de Zeeuw, Dick

Journal:

American Journal of Kidney Diseases

Year:

2014

Language:

english

File:

PDF, 729 KB

english, 2014

35

The effect of RAAS blockade on the progression of diabetic nephropathy

Roscioni, Sara S., Heerspink, Hiddo J. Lambers, de Zeeuw, Dick

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2014

File:

PDF, 514 KB

2014

36

A novel approach for establishing cardiovascular drug efficacy

Heerspink, Hiddo. J. Lambers, Grobbee, Diederick E., de Zeeuw, Dick

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 613 KB

english, 2014

37

Cardiovascular disease in patients with chronic kidney disease

Pilmore, Helen, Dogra, Gursharan, Roberts, Matthew, Lambers Heerspink, Hiddo J, Ninomiya, Toshiharu, Huxley, Rachel, Perkovic, Vlado

Journal:

Year:

2014

Language:

english

File:

PDF, 129 KB

english, 2014

38

GFR Decline as an Alternative End Point to Kidney Failure in Clinical Trials: A Meta-analysis of Treatment Effects From 37 Randomized Trials

Inker, Lesley A., Lambers Heerspink, Hiddo J., Mondal, Hasi, Schmid, Christopher H., Tighiouart, Hocine, Noubary, Farzad, Coresh, Josef, Greene, Tom, Levey, Andrew S.

Journal:

American Journal of Kidney Diseases

Year:

2014

Language:

english

File:

PDF, 606 KB

english, 2014

39

GFR Decline and Subsequent Risk of Established Kidney Outcomes: A Meta-analysis of 37 Randomized Controlled Trials

Lambers Heerspink, Hiddo J., Tighiouart, Hocine, Sang, Yingying, Ballew, Shoshana, Mondal, Hasi, Matsushita, Kunihiro, Coresh, Josef, Levey, Andrew S., Inker, Lesley A.

Journal:

American Journal of Kidney Diseases

Year:

2014

Language:

english

File:

PDF, 370 KB

english, 2014

40

Microalbuminuria: target for renoprotective therapy PRO

Roscioni, Sara S, Lambers Heerspink, Hiddo J, de Zeeuw, Dick

Journal:

Kidney International

Year:

2014

Language:

english

File:

PDF, 622 KB

english, 2014

41

Moderation of dietary sodium potentiates the renal and cardiovascular protective effects of angiotensin receptor blockers

Heerspink, Hiddo J Lambers, Holtkamp, Frank A, Parving, Hans-Henrik, Navis, Gerjan J, Lewis, Julia B, Ritz, Eberhard, de Graeff, Pieter A, de Zeeuw, Dick

Journal:

Kidney International

Year:

2012

Language:

english

File:

PDF, 279 KB

english, 2012

42

The Authors Reply:

Heerspink, Hiddo J Lambers, Holtkamp, Frank A, De Zeeuw, Dick

Journal:

Kidney International

Year:

2012

Language:

english

File:

PDF, 78 KB

english, 2012

43

Clinical trials: New nonabsorbable potassium-exchange resins in hyperkalaemia

Roscioni, Sara S., Heerspink, Hiddo J. Lambers

Journal:

Nature Reviews Nephrology (formerly Nature Clinical Practice Nephrology)

Year:

2015

Language:

english

File:

PDF, 115 KB

english, 2015

44

Fibroblast Growth Factor 23 and the Antiproteinuric Response to Dietary Sodium Restriction During Renin-Angiotensin-Aldosterone System Blockade

Humalda, Jelmer K., Lambers Heerspink, Hiddo J., Kwakernaak, Arjan J., Slagman, Maartje C.J., Waanders, Femke, Vervloet, Marc G., Ter Wee, Pieter M., Navis, Gerjan, de Borst, Martin H.

Journal:

American Journal of Kidney Diseases

Year:

2015

Language:

english

File:

PDF, 398 KB

english, 2015

45

Proteinuria in Type 2 Diabetic Patients with Renal Impairment: The Changing Face of Diabetic Nephropathy

Packham, David K., Ivory, Sara E., Reutens, Anne T., Wolfe, Rory, Rohde, Richard, Lambers Heerspink, Hiddo, Dwyer, Jamie P., Atkins, Robert C., Lewis, Julia

Journal:

Nephron Clinical Practice

Year:

2011

Language:

english

File:

PDF, 632 KB

english, 2011

46

PS12 Cont’d - 62. Prescribing of aliskiren in practice: findings from the GIANTT diabetes

Voorham, Jaco, Mol, Peter G.M., Lambers Heerspink, Hiddo J., de Zeeuw, Dick, Denig, Petra

Journal:

Nederlands Tijdschrift voor Diabetologie

Year:

2012

Language:

english

File:

PDF, 308 KB

english, 2012

47

PS11 - 1. Longitudinal eGFR trajectories in patients with type 2 diabetes

Weldegiorgis, Misghina, de Zeeuw, Dick, Greene, Tom, Li, Liang, Rossing, Peter, Smink, Paul, Heerspink, Hiddo Lambers

Journal:

Nederlands Tijdschrift voor Diabetologie

Year:

2013

Language:

english

File:

PDF, 233 KB

english, 2013

48

Pleiotropic effects of type 2 diabetes management strategies on renal risk factors

Muskiet, Marcel H A, Tonneijck, Lennart, Smits, Mark M, Kramer, Mark H H, Heerspink, Hiddo J Lambers, van Raalte, Daniël H

Journal:

The Lancet Diabetes & Endocrinology

Year:

2015

Language:

english

File:

PDF, 227 KB

english, 2015

49

Serum Bicarbonate and Kidney Disease Progression and Cardiovascular Outcome in Patients With Diabetic Nephropathy: A Post Hoc Analysis of the RENAAL (Reduction of End Points in Non–Insulin-Dependent Diabetes With the Angiotensin II Antagonist Losartan) Study and IDNT (Irbesartan Diabetic Nephropathy Trial)

Schutte, Elise, Lambers Heerspink, Hiddo J., Lutgers, Helen L., Bakker, Stephan J.L., Vart, Priya, Wolffenbuttel, Bruce H.R., Umanath, Kausik, Lewis, Julia B., de Zeeuw, Dick, Gansevoort, Ron T.

Journal:

American Journal of Kidney Diseases

Year:

2015

Language:

english

File:

PDF, 579 KB

english, 2015

50

Cardiovascular endocrinology: Dual RAAS blockade has dual effects on outcome

Heerspink, Hiddo J. Lambers, de Zeeuw, Dick

Journal:

Nature Reviews Endocrinology (formerly Nature Clinical Practice Endocrinology & Metabolism)

Year:

2013

Language:

english

File:

PDF, 678 KB

english, 2013

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